● Oncology
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Tib neeg Methylated NDRG4/SEPT9/SFRP2/BMP3/SDC2 Gene
Cov khoom siv yog npaj rau hauv vitro zoo nrhiav pom ntawm methylated NDRG4 / SEPT9 / SFRP2 / BMP3 / SDC2 noob nyob rau hauv cov hnyuv exfoliated hlwb hauv tib neeg cov quav.
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Tib neeg BRAF Gene V600E Mutation
Cov khoom siv kuaj no yog siv los ntsuas qhov zoo ntawm BRAF gene V600E kev hloov pauv hauv paraffin-embedded cov ntaub so ntswg ntawm tib neeg melanoma, mob qog noj ntshav, qog nqaij hlav qog noj ntshav thiab mob ntsws cancer hauv vitro.
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Tib neeg BCR-ABL Fusion Gene Mutation
Cov khoom siv no tsim nyog rau kev kuaj pom zoo ntawm p190, p210 thiab p230 isoforms ntawm BCR-ABL fusion gene hauv tib neeg cov pob txha pob txha.
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KRAS 8 Mutations
Cov khoom siv no yog npaj rau hauv vitro zoo nrhiav pom ntawm 8 kev hloov pauv hauv codons 12 thiab 13 ntawm K-ras gene hauv cov DNA rho tawm los ntawm tib neeg paraffin-embedded pathological seem.
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Tib neeg EGFR Gene 29 Mutations
Cov khoom siv no yog siv rau hauv vitro qualitatively nrhiav tau ntawm kev hloov pauv hauv exons 18-21 ntawm EGFR noob hauv cov qauv los ntawm tib neeg cov neeg mob qog noj ntshav tsis me me.
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Human ROS1 Fusion Gene Mutation
Cov khoom siv no yog siv rau hauv vitro qualitative nrhiav tau ntawm 14 hom ROS1 fusion gene mutations nyob rau hauv tib neeg uas tsis yog-me me cell mob qog nqaij hlav (Table 1).Cov txiaj ntsig kev xeem no tsuas yog siv rau kev kho mob nkaus xwb thiab yuav tsum tsis txhob siv los ua ib lub hauv paus rau kev kho tus kheej ntawm cov neeg mob.
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Tib neeg EML4-ALK Fusion Gene Mutation
Cov khoom siv no yog siv los soj ntsuam 12 yam kev hloov pauv ntawm EML4-ALK fusion gene hauv cov qauv ntawm tib neeg cov neeg mob ntsws cancer hauv vitro.Cov txiaj ntsig kev xeem no tsuas yog siv rau kev kho mob nkaus xwb thiab yuav tsum tsis txhob siv los ua ib lub hauv paus rau kev kho tus kheej ntawm cov neeg mob.Cov kws kho mob yuav tsum txiav txim siab tag nrho ntawm cov txiaj ntsig kev xeem raws li cov xwm txheej xws li tus neeg mob tus mob, cov tshuaj qhia tshuaj, cov lus teb rau kev kho mob, thiab lwm yam ntsuas ntsuas ntsuas.
