KRAS 8 Mutations

Lus piav qhia luv luv:

Cov khoom siv no yog npaj rau hauv vitro zoo nrhiav pom ntawm 8 kev hloov pauv hauv codons 12 thiab 13 ntawm K-ras gene hauv cov DNA rho tawm los ntawm tib neeg paraffin-embedded pathological seem.


Product Detail

Khoom cim npe

Khoom npe

HWTS-TM014-KRAS 8 Mutations Detection Kit (Fluorescence PCR)

HWTS-TM011-Freeze-dried KRAS 8 Mutations Detection Kit (Fluorescence PCR)

Daim ntawv pov thawj

CE

Kab mob sib kis

Kev hloov pauv hauv KRAS cov noob tau pom nyob rau hauv ntau hom qog nqaij hlav hauv tib neeg, txog 17% ~ 25% kev hloov pauv hauv cov qog, 15% ~ 30% kev hloov pauv hauv cov neeg mob qog noj ntshav, 20% ~ 50% kev hloov pauv hauv cov qog nqaij hlav cancer. cov neeg mob.Vim hais tias P21 protein encoded los ntawm K-ras noob nyob rau hauv downstream ntawm EGFR signaling txoj kev, tom qab lub K-ras noob kev hloov, txoj kev downstream signaling yog ib txwm qhib thiab tsis cuam tshuam los ntawm cov upstream targeted tshuaj ntawm EGFR, ua rau tsis tu ncua. malignant proliferation ntawm cell.Kev hloov pauv hauv K-ras noob feem ntau pom zoo rau EGFR tyrosine kinase inhibitors hauv cov neeg mob qog noj ntshav thiab tsis kam tiv thaiv EGFR tshuaj tiv thaiv kab mob hauv cov neeg mob qog noj ntshav.Xyoo 2008, National Comprehensive Cancer Network (NCCN) tau tshaj tawm cov lus qhia txog kev kho mob rau cov qog nqaij hlav hauv plab, uas tau taw qhia tias qhov chaw hloov pauv uas ua rau K-ras tau ua haujlwm feem ntau yog nyob hauv codons 12 thiab 13 ntawm exon 2, thiab pom zoo tias. Txhua tus neeg mob uas muaj mob qog noj ntshav siab metastatic tuaj yeem kuaj K-ras kev hloov ua ntej kev kho mob.Yog li ntawd, kev tshawb nrhiav sai thiab raug ntawm K-ras noob hloov yog qhov tseem ceeb hauv kev qhia tshuaj kho mob.Cov khoom siv no siv DNA ua tus qauv kuaj pom los muab kev ntsuas zoo ntawm kev hloov pauv, uas tuaj yeem pab cov kws kho mob hauv kev kuaj mob qog noj ntshav, mob qog noj ntshav thiab lwm cov qog nqaij hlav uas tau txais txiaj ntsig los ntawm cov tshuaj tsom.Cov txiaj ntsig ntawm cov khoom siv yog siv rau kev soj ntsuam nkaus xwb thiab yuav tsum tsis txhob siv los ua lub hauv paus rau kev kho tus kheej ntawm cov neeg mob.Cov kws kho mob yuav tsum txiav txim siab tag nrho ntawm cov txiaj ntsig kev ntsuas raws li cov xwm txheej xws li tus neeg mob tus mob, cov tshuaj qhia tshuaj, cov lus teb kho mob thiab lwm yam ntsuas ntsuas ntsuas.

Technical Parameters

Cia Ua kua: ≤-18 ℃ Hauv qhov tsaus ntuj;Lyophilized: ≤30 ℃ Hauv qhov tsaus ntuj
Txee lub neej Kua: 9 lub hlis;Lyophilized: 12 lub hlis
Hom Qauv paraffin-embedded pathological cov ntaub so ntswg los yog seem muaj cov qog hlwb
CV ≤ 5.0%
LoD K-ras Reaction Buffer A thiab K-ras Reaction Buffer B tuaj yeem txheeb xyuas 1% kev hloov pauv hauv qab 3ng / μL hom tsiaj qus tom qab
Cov cuab yeej siv tau Siv Biosystems 7500 Real-Time PCR Systems

Siv Biosystems 7300 Real-Time PCR Systems

QuantStudio®5 Real-Time PCR Systems

LightCycler® 480 Real-Time PCR system

BioRad CFX96 Real-Time PCR System

Ua hauj lwm Flow

Nws raug pom zoo kom siv QIAGEN's QIAamp DNA FFPE Tissue Kit (56404) thiab Paraffin-embedded Tissue DNA Rapid Extraction Kit (DP330) tsim los ntawm Tiangen Biotech (Beijing) Co., Ltd.


  • Yav dhau los:
  • Tom ntej:

  • Sau koj cov lus ntawm no thiab xa tuaj rau peb