Progesterone (P)

Progesterone yog ib qho tseem ceeb progestogen, teej tug mus rau steroid hormones, nrog ib tug txheeb ze molecular hnyav ntawm 314.5.Nws yog tsim los ntawm corpus luteum ntawm zes qe menyuam thiab placenta thaum cev xeeb tub.Nws yog tus precursor ntawm testosterone, estrogen thiab adrenal cortex cov tshuaj hormones.Cov qib progesterone uas tsim tawm thaum lub sij hawm follicular theem ntawm cov txiv neej thiab cov poj niam yog tsawg heev, tom qab tso rau hauv cov ntshav, nws yog feem ntau khi rau albumin thiab poj niam txiv neej cov tshuaj hormones khi protein thiab circulating nyob rau hauv lub cev.

Lub luag haujlwm tseem ceeb ntawm progesterone yog ua kom lub tsev menyuam npaj rau kev cog cov qe fertilized thiab tswj kev xeeb tub.Thaum lub sij hawm follicular theem ntawm kev coj khaub ncaws, qib progesterone tsawg.Tom qab ovulation, progesterone tsim los ntawm corpus luteum nce sai, thiab nce mus txog qhov siab tshaj plaws ntawm 10ng / mL-20ng / mL hauv 5-7 hnub tom qab ovulation.Yog tias tsis xeeb tub, corpus luteum atrophies thaum plaub hnub dhau los ntawm kev coj khaub ncaws thiab cov progesterone concentration txo mus rau theem follicular.Yog tias xeeb tub, lub corpus luteum tsis ploj mus thiab txuas ntxiv zais cov progesterone, ua kom nws nyob rau theem sib npaug rau theem nruab nrab luteal thiab txuas ntxiv mus txog rau lub lim tiam thib rau ntawm cev xeeb tub.Thaum cev xeeb tub, cov placenta maj mam dhau los ua qhov tseem ceeb ntawm progesterone, thiab cov concentration nce ntawm 10ng / mL-50ng / mL hauv thawj 3 lub hlis ntawm cev xeeb tub mus txog 50ng / mL-280ng / mL hauv 7-9 lub hlis.Cov kev tshawb fawb soj ntsuam tau pom tias progesterone ua lub luag haujlwm hauv kev txhawb nqa ovulation thiab tswj kev ua haujlwm ib txwm muaj ntawm corpus luteum hauv cov poj niam uas tsis cev xeeb tub.Yog hais tias cov progesterone tsim los ntawm corpus luteum tsis txaus, nws yuav qhia tau hais tias corpus luteum muaj nuj nqi tsis txaus, thiab tsis txaus corpus luteum muaj feem xyuam rau infertility thiab thaum ntxov nchuav menyuam.