Mycobacterium Tuberculosis INH Resistance

Lus piav qhia luv luv:

Cov khoom siv no yog siv los txheeb xyuas cov noob hloov pauv ntawm 315th amino acid ntawm katG gene (K315G>C) thiab cov noob hloov pauv ntawm thaj chaw txhawb nqa ntawm InhA gene (- 15 C> T).

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Product Detail

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HWTS-RT002A-Mycobacterium Tuberculosis Isoniazid Resistance Detection Kit (Fluorescence PCR)

Kab mob sib kis

Isoniazid, ib qho tshuaj tiv thaiv kab mob tseem ceeb tshaj tawm hauv xyoo 1952, yog ib qho tshuaj zoo tshaj plaws rau kev kho mob ntawm tuberculosis ua ke thiab ib qho tshuaj rau cov tuberculosis latent.

KatG yog lub ntsiab gene encoding catalase-peroxidase thiab katG noob hloov tuaj yeem txhawb kev sib txuas ntawm mycolic acid cell phab ntsa, ua rau cov kab mob tiv taus isoniazid.KatG kev qhia tsis zoo cuam tshuam nrog kev hloov pauv hauv INH-MIC, thiab 2-fold txo ntawm katG qhia ua rau me ntsis loj dua 2-fold nce hauv MIC.Lwm qhov ua rau isoniazid tsis kam nyob rau hauv mycobacterium tuberculosis tshwm sim thaum lub hauv paus ntxig, tshem tawm lossis hloov pauv tshwm sim hauv InhA gene locus ntawm mycobacterium tuberculosis.

Channel

ROX	inhA (-15C>T) site·
CY 5	katG (315G>C) site
VIC (HEX)	TIAB SA 6110

Technical Parameters

Cia	≤-18 ℃ Hauv qhov tsaus ntuj
Txee lub neej	12 hli
Hom Qauv	Cov hnoos qeev
CV	≤ 5.0%
LoD	1 × 10³kab mob / ml
Qhov tshwj xeeb	Tsis muaj kev sib cuam tshuam nrog kev hloov pauv ntawm plaub qhov chaw tiv thaiv tshuaj (511, 516, 526 thiab 531) ntawm rpoB gene sab nraum qhov kev tshawb pom ntau ntawm cov khoom siv tshawb nrhiav. Cov cuab yeej siv tau: Siv Biosystems 7500 Real-Time PCR Systems Siv Biosystems 7500 Fast Real-Time PCR Systems QuantStudio®5 Real-Time PCR Systems SLAN-96P Real-Time PCR Systems LightCycler® 480 Real-Time PCR system LineGene 9600 Plus Real-Time PCR Detection System MA-6000 Real-Time Quantitative Thermal Cycler BioRad CFX96 Real-Time PCR System BioRad CFX Opus 96 Real-Time PCR System