MTHFR Gene Polymorphic Nucleic Acid
Khoom npe
HWTS-GE004-MTHFR Gene Polymorphic Nucleic Acid Detection Kit (ARMS-PCR)
Kab mob sib kis
Folic acid yog dej-soluble vitamin uas yog ib qho tseem ceeb cofactor nyob rau hauv lub cev txoj kev metabolic.Nyob rau hauv xyoo tas los no, ntau cov kev tshawb fawb tau lees paub tias, kev hloov pauv ntawm folate metabolizing enzyme gene MTHFR yuav ua rau lub cev tsis muaj folic acid hauv lub cev, thiab kev puas tsuaj ntawm folic acid nyob rau hauv cov neeg laus yuav ua rau megaloblastic anemia, vascular. endothelial puas, thiab lwm yam. Folic acid deficiency hauv cov poj niam cev xeeb tub tsis tuaj yeem ua tau raws li qhov xav tau ntawm lawv tus kheej thiab tus menyuam hauv plab, uas tuaj yeem ua rau cov hlab ntsha neural tsis xws luag, anencephaly, tseem yug menyuam, thiab nchuav menyuam.Cov qib folate hauv cov ntshav tau cuam tshuam los ntawm 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms.Qhov 677C>T thiab 1298A>C kev hloov pauv hauv MTHFR noob ua rau kev hloov pauv ntawm alanine rau valine thiab glutamic acid, raws li, ua rau txo qis MTHFR kev ua haujlwm thiab ua rau txo kev siv folic acid.
Channel
| FAM | MTHFR C677T |
| ROX | MTHFR A1298C |
| VIC (HEX) | Internal tswj |
Technical Parameters
| Cia | ≤-18 ℃ |
| Txee lub neej | 12 hli |
| Hom Qauv | Freshly sau EDTA anticoagulated ntshav |
| CV | ≤ 5.0% |
| Ct | ≤38 |
| LoD | 1.0 ng / μL |
| Cov cuab yeej siv tau: | Siv Biosystems 7500 Real-Time PCR Systems Siv Biosystems 7500 Fast Real-Time PCR Systems SLAN ®-96P Real-Time PCR Systems QuantStudio™ 5 Real-Time PCR Systems LightCycler® 480 Real-Time PCR system LineGene 9600 Plus Real-Time PCR Detection System MA-6000 Real-Time Quantitative Thermal Cycler BioRad CFX96 Real-Time PCR System BioRad CFX Opus 96 Real-Time PCR System |
Ua hauj lwm Flow
Kev xaiv 1
Pom zoo extraction reagents: Macro & Micro-Test Genomic DNA Kit (HWTS-3014-32, HWTS-3014-48, HWTS-3014-96) thiab Macro & Micro-Test Automatic Nucleic Acid Extractor (HWTS-3006C, HWTS-3006B) .
Kev xaiv 2
Pom zoo extraction reagents: Ntshav Genomic DNA Extraction Kit (YDP348, JCXB20210062) los ntawm Tiangen Biotech (Beijing) Co., Ltd.Ntshav Genome Extraction Kit (A1120) los ntawm Promega.
